O'Grady

O'Grady is a 2004 Flash animated series that aired on the teen oriented Noggin block, The N (later TeenNick) and MTV Latin America. The show follows Kevin Harnisch, Harold Jenkins, Abby Wilde and Beth Briggs as they deal with a phenomenal supernatural force, called "The Weirdness" that affects their eponymous hometown in strange but comedic ways, while going to high school facing everyday life. O'Grady was cancelled after only 19 episode, but reran from 2007 to 2008 and briefly in mid-2013.

"Sweats"

The Weirdness makes one's insecurity physically blow up if their sweat comes in contact. Towards the episode's climax, Kevin helps Harold win a wrestling match the he worried over (after suffering from a reverse effect with the Weirdness) as his sweat drips onto his torso, giving him a sumo-like buff-up. As usual, Harold, and all the other victims of the Weirdness snap back to normal before the next episode.